NEURAL CIRCUIT MODELING
Introduction: Neurology is the study of Brain and the related organs. This is being studied by various ways namely anatomically, physiologically, biochemically, clinically and in therapeutic angles. Clinically central nervous system, peripheral nervous system and autonomic nervous system are the compartments of study of Neurology. Some are adding the hypophysis (Pituitary glands) and its functions along with the already mentioned parts.So, when a planning is to be made for the development of a modeling for neural circuit which should bring in maximum information for the academicians and research workers, the above factors need to be taken into account.
Aim of this study: Brain is an important organ of the body and is rightly christened as the master orchestra of the body. The brain is studied Anatomically, Physiologically,
Pathologically and Clinically both in Neuro Medicine and Neuro Surgically in a detailed way from the days of Hippocrates of Western world and also in India during the period of Agastiar like Siddhars in Tamil Nadu and Susrutha and Charaka in North India. With the advent of modern imaging equipments in the field of neurology, the decision making in Neuroscience has become a child’s play related to Diagnosis. But in the field of Neurology and Neuro Surgery, the treatment aspects are improving and the perfection of doing treatment even in the case of one of the oldest diseases of the world namely Epilepsy is yet to be perfect.
The study of Neuroscience is going in a molecular level and piece meal and industry driven and synthesis of the details available are not done routinely by anybody as was the case some decades ago due to non availability of selfless basic workers in Neuroscience today as like that of yester centuries.So, quantitatively there is leaf and bounds of application development in Neurosciences due to commercial reasons but basic concept development is at stagnant level. So, like that of table of Elements in Chemistry and classification in Zoology and Botany we need to create an uniform information applicable at all disorders of Neurology. An attempt is made to create such a theory applicable to all disorders of Neurology for better understanding of the symptoms and signs and also the pathology in a different perspective which is not conventionally followed in medicine. This will lead to better planning for management, predictability of prognosis and outcome or morbidity and mortality and future development of better therapies.
The present study is to making a model for this concept namely
Doctor Shanmugam’s Theory of Brain Behaviors in Disorders
using computer aided programme which once worked out will be an easy approach for the diagnosis of neurological diseases within a short span of time and with out observer bias for predicting the symptoms, signs and the outcome of the therapy. The details will be highlighted in the lecture.
With these, let us discuss the details of the theory.
Brain behavior in disorders can be defined with the following criteria:
1. Position of the lesion in brain: Central lesions produce more symptoms and signs. Peripheral lesions produce less symptoms and signs
“Centre the lesion more are the symptoms and signs and peripheral the lesion less are the symptoms and signs.( SHANMUGAM’s First law of brain behavior)
2. Size of the lesion: Even smaller lesions in midline can produce more symptoms and signs than expected
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